Dr Eddison Loades
Research Associate
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Research
I am a biochemist with a keen interest in understanding the molecular mechanisms underlying ribosome stalling and translation regulation. My research focuses on integrating advanced molecular techniques to explore how cells regulate protein synthesis in response to stress.
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Awards, Degrees, Honours
BSc, MSc, PhD
Profile
My research investigates ribosome stalling mechanisms in Schizosaccharomyces pombe, with a particular focus on identifying codons where stalling occurs and understanding the molecular processes governing this phenomenon. I employ techniques such as Orthogonal Organic Phase Separation (OOPS), tRNA-seq, ribosome profiling (ribo-seq), CRISPR, reporter constructs and proteomics to study ribosome-protein interactions and RNA-protein dynamics in stress conditions. The combination of genomic, proteomic and metabolomic approaches will reveal general principles applicable to higher eukaryotes.
I also supervise Part II and Part III research projects within the Natural Sciences Tripos.
Feel free to reach out - I’m always eager to discuss science, explore collaborations and opportunities, and connect with new people!